Compound Q&A
How is 1-[(4-Methylphenyl)sulfonyl]-1H-1,2,4-triazole (CAS: 13578-51-3) typically synthesized?
Answer
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1-[(4-Methylphenyl)sulfonyl]-1H-1,2,4-triazole (CAS: 13578-51-3) can be synthesized through a multistep process involving the coupling of 4-methylphenylsulfonyl chloride with 1,2,4-triazole. This reaction typically requires a suitable base, such as sodium hydroxide, and is performed in an aprotic solvent like dimethylformamide (DMF). The yield is generally good, and the method is scalable for industrial production.
About
CAS No
13578-51-3
English Name
1-[(4-Methylphenyl)sulfonyl]-1H-1,2,4-triazole
Molecular Formula
C9H9N3O2S
Molecular Weight
223.26 g/mol
SMILES
CC1=CC=C(C=C1)S(=O)(=O)N2C=NC=N2
InChIKey
GFWABQNSSIQCLB-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
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