Compound Q&A

How is (17alpha)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one (CAS: 5630-53-5) typically synthesized?

Answer

(17alpha)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one
(17alpha)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one is commonly synthesized through a series of reactions starting from a suitable steroidal precursor. The process involves hydroxylation, methylation, and alkynylation steps. Palladium catalysts are often used for the arylation and hydroxylation reactions, achieving high selectivity and yield. The final product is purified through recrystallization or column chromatography.

About

CAS No 5630-53-5
English Name (17alpha)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one
Molecular Formula C21H28O2
Molecular Weight 312.4 g/mol
SMILES CC1CC2=C(CCC(=O)C2)C3C1C4CCC(C4(CC3)C)(C#C)O
InChIKey WZDGZWOAQTVYBX-XOINTXKNSA-N
Last Updated: 2025-10-20 00:35

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