Compound Q&A

How is 4,4,4-Trifluorobutanal (CAS: 406-87-1) typically synthesized?

Answer

4,4,4-Trifluorobutanal
4,4,4-Trifluorobutanal can be synthesized through the oxidative cleavage of 1,1,1-trifluoro-3-butanone using osmium tetroxide and acetone as catalysts. This method provides good yield and selectivity for the aldehyde product. Other routes include the reduction of trifluoroacetaldehyde with hydrogen over a metal catalyst.

About

CAS No 406-87-1
English Name 4,4,4-Trifluorobutanal
Molecular Formula C4H5F3O
Molecular Weight 126.08 g/mol
SMILES C(CC(F)(F)F)C=O
InChIKey SCJCDNUXDWFVFI-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

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