4,4,4-Trifluorobutanal(CAS: 406-87-1)

4,4,4-Trifluorobutanal (CAS: 406-87-1) is a colorless liquid with a strong, pungent odor. It has a molecular weight of 130.06 g/mol and a boiling point of 95-97°C. The compound is slightly soluble in water but highly soluble in organic solvents. It is moderately reactive, particularly with nucleophiles, and can undergo keto-enol tautomerism.

4,4,4-Trifluorobutanal can be synthesized through the oxidative cleavage of 1,1,1-trifluoro-3-butanone using osmium tetroxide and acetone as catalysts. This method provides good yield and selectivity for the aldehyde product. Other routes include the reduction of trifluoroacetaldehyde with hydrogen over a metal catalyst.

4,4,4-Trifluorobutanal (CAS: 406-87-1) is used in the pharmaceutical industry for the synthesis of certain drugs due to its unique functional groups. It is also utilized in the polymer industry as a monomer for specialized polymers. Additionally, it has applications in sensors and semiconductors for its chemical reactivity and functional properties.

When handling 4,4,4-Trifluorobutanal (CAS: 406-87-1), ensure the use of appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood. Store the compound in a cool, dry place away from heat sources and direct sunlight. In case of spill, refer to the safety data sheet (SDS) for proper handling instructions and clean up using appropriate absorbents.