Compound Q&A
How is Fosfluconazole (CAS: 194798-83-9) typically synthesized?
Answer
Fosfluconazole (CAS: 194798-83-9) is typically synthesized through a multi-step process involving amidation and cyclization reactions. The synthesis begins with the transformation of a fluconazole derivative into a key intermediate, followed by amidation with 2-fluorobenzylamine. The final product is obtained through a cyclization step. Common catalysts include triphenylphosphine and other organophosphorus compounds, with yields typically ranging from 60% to 70%.
About
CAS No
194798-83-9
English Name
Fosfluconazole
Molecular Formula
C13H13F2N6O4P
Molecular Weight
386.25 g/mol
SMILES
C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)OP(=O)(O)O
InChIKey
GHJWNRRCRIGGIO-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30
