Compound Q&A
How is 5-(Benzyloxy)-2,4-dichloropyrimidine (CAS: 91183-17-4) typically synthesized?
Answer
5-(Benzyloxy)-2,4-dichloropyrimidine (CAS: 91183-17-4) can be synthesized through a multistep process involving the protection of a chloropyrimidine with a benzyloxy group followed by deprotection. Common synthetic methods include the use of benzyloxycarbonyl (Boc) protection, which is then removed using trifluoroacetic acid (TFA). The overall yield can be around 60-70%, with high regioselectivity and chemoselectivity.
About
CAS No
91183-17-4
English Name
5-(Benzyloxy)-2,4-dichloropyrimidine
Molecular Formula
C11H8Cl2N2O
Molecular Weight
255.1 g/mol
SMILES
C1=CC=C(C=C1)COC2=CN=C(N=C2Cl)Cl
InChIKey
HICKLOUBWJHHFE-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30
