Compound Q&A

How is 2,4-Difluoro-1-(trifluoromethyl)benzene (CAS: 64248-61-9) typically synthesized?

Answer

2,4-Difluoro-1-(trifluoromethyl)benzene
2,4-Difluoro-1-(trifluoromethyl)benzene is typically synthesized through the Friedel-Crafts alkylation of 2,4-difluorotoluene using trifluoromethylating agents like trifluoromethyl sulfonic acid. This process involves the use of Lewis acids as catalysts and requires precise temperature control to achieve good selectivity and yield.

About

CAS No 64248-61-9
English Name 2,4-Difluoro-1-(trifluoromethyl)benzene
Molecular Formula C7H3F5
Molecular Weight 182.09 g/mol
SMILES C1=CC(=C(C=C1F)F)C(F)(F)F
InChIKey PQJOLFTWPSZESR-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

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