Compound Q&A
How is (3aR,6aS)-Tetrahydro-1H-cyclopenta[c]furan-1,3(3aH)-dione (CAS: 35878-28-5) typically synthesized?
Answer
![(3aR,6aS)-Tetrahydro-1H-cyclopenta[c]furan-1,3(3aH)-dione](https://static.chemtradehub.com/structs/358/35878-28-5-54ea.webp "(3aR,6aS)-Tetrahydro-1H-cyclopenta[c]furan-1,3(3aH)-dione")
(3aR,6aS)-Tetrahydro-1H-cyclopenta[c]furan-1,3(3aH)-dione can be synthesized via the Wittig reaction or the Claisen condensation of appropriate precursors. The Wittig reaction involves the reaction of an aldehyde or ketone with a phosphonium ylide, while the Claisen condensation requires an ester and a phenol. The yield can be up to 80-90%, with good regioselectivity and stereoselectivity.
About
CAS No
35878-28-5
English Name
(3aR,6aS)-Tetrahydro-1H-cyclopenta[c]furan-1,3(3aH)-dione
Molecular Formula
C7H8O3
Molecular Weight
140.14 g/mol
SMILES
C1CC2C(C1)C(=O)OC2=O
InChIKey
NMSRALOLNIBERV-SYDPRGILSA-N
Last Updated: 2025-10-19 20:30
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