Compound Q&A

How is (5-Chloro-2-pyrazinyl)methanol (CAS: 72788-94-4) typically synthesized?

Answer

(5-Chloro-2-pyrazinyl)methanol
(5-Chloro-2-pyrazinyl)methanol can be synthesized through the reaction of 2-chloropyrazine with methanol in the presence of a base such as potassium hydroxide. The reaction is typically conducted in an inert atmosphere to prevent side reactions. The yield can be improved by using appropriate reaction conditions and catalysts.

About

CAS No 72788-94-4
English Name (5-Chloro-2-pyrazinyl)methanol
Molecular Formula C5H5ClN2O
Molecular Weight 144.56 g/mol
SMILES C1=C(N=CC(=N1)Cl)CO
InChIKey YUTQYZGRAJOIJV-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

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