Compound Q&A

How is (2,6-Dichloro-4-pyridinyl)boronic acid (CAS: 1072951-54-2) typically synthesized?

Answer

(2,6-Dichloro-4-pyridinyl)boronic acid
(2,6-Dichloro-4-pyridinyl)boronic acid is commonly synthesized via the reaction of 2,6-dichloropyridine with boron tribromide followed by treatment with a base. The reaction is catalyzed by a Lewis acid and proceeds with high selectivity, yielding a high purity product with a yield of about 75-80%.

About

English Name (2,6-Dichloro-4-pyridinyl)boronic acid
Molecular Formula C5H4BCl2NO2
Molecular Weight 191.81 g/mol
SMILES OB(c1cc(Cl)nc(c1)Cl)O
InChIKey JFUQZFQJFYZZGY-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:29

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