Compound Q&A

How is 1-(2-Chloroethoxy)-4-nitrobenzene (CAS: 3383-72-0) typically synthesized?

Answer

1-(2-Chloroethoxy)-4-nitrobenzene
1-(2-Chloroethoxy)-4-nitrobenzene (CAS: 3383-72-0) can be synthesized via the Grignard reaction, where 2-chloroethanol reacts with 4-nitrobenzyl bromide in the presence of a Grignard reagent. This method provides good yield and control over the reaction conditions. Other synthetic routes involve the use of diazonium salts and subsequent coupling reactions.

About

CAS No 3383-72-0
English Name 1-(2-Chloroethoxy)-4-nitrobenzene
Molecular Formula C8H8ClNO3
Molecular Weight 201.61 g/mol
SMILES C1=CC(=CC=C1[N+](=O)[O-])OCCCl
InChIKey OBCFOPGCTNULTG-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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