Compound Q&A
How is 2-Chloro-5-Fluoropyridine-3-carbaldehyde (CAS: 851484-95-2) typically synthesized?
Answer
2-Chloro-5-Fluoropyridine-3-carbaldehyde is typically synthesized via the acylation of 2-chloro-5-fluoropyridine with acetaldehyde in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction is carried out under reflux, and high yields (up to 80%) can be achieved under optimized conditions. The reaction is highly selective and produces a single product with good purity.
About
CAS No
851484-95-2
English Name
2-Chloro-5-Fluoropyridine-3-carbaldehyde
Molecular Formula
C6H3ClFNO
Molecular Weight
159.55 g/mol
SMILES
C1=C(C=NC(=C1C=O)Cl)F
InChIKey
IMQFWCDQEAIYJV-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36
