Compound Q&A

How is 2-Methyl-2-propanyl (5-bromo-1,3-thiazol-2-yl)carbamate (CAS: 405939-39-1) typically synthesized?

Answer

2-Methyl-2-propanyl (5-bromo-1,3-thiazol-2-yl)carbamate
2-Methyl-2-propanyl (5-bromo-1,3-thiazol-2-yl)carbamate is typically synthesized through nucleophilic substitution reactions. Bromoacetamide is reacted with 2-methyl-2-propanol in the presence of a suitable base, such as potassium carbonate, followed by the addition of 5-bromo-1,3-thiazole-2-carbonyl chloride. The yield is generally around 70-80%, and the reaction is selective towards the carbamate formation.

About

English Name 2-Methyl-2-propanyl (5-bromo-1,3-thiazol-2-yl)carbamate
Molecular Formula C8H11BrN2O2S
Molecular Weight 279.16 g/mol
SMILES CC(C)(C)OC(=O)NC1=NC=C(S1)Br
InChIKey OIBKBVFFZYCBAQ-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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