Compound Q&A

How is 5-Bromo-1,2-benzoxazole (CAS: 837392-65-1) typically synthesized?

Answer

5-Bromo-1,2-benzoxazole
5-Bromo-1,2-benzoxazole (CAS: 837392-65-1) is typically synthesized via bromination of 1,2-benzoxazole using N-bromosuccinimide (NBS) in the presence of a suitable organic solvent such as chloroform. The reaction is carried out under UV light, and the product can be isolated by recrystallization from water or ethanol. The yield is generally around 70-80%, and the reaction is highly selective.

About

English Name 5-Bromo-1,2-benzoxazole
Molecular Formula C7H4BrNO
Molecular Weight 198.02 g/mol
SMILES Brc1ccc2oncc2c1
InChIKey XAGKLUNARLSYDT-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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