Compound Q&A

How is 1-(4-Hydroxyphenyl)thiourea (CAS: 1520-27-0) typically synthesized?

Answer

1-(4-Hydroxyphenyl)thiourea
1-(4-Hydroxyphenyl)thiourea is typically synthesized via the condensation of 4-hydroxyaniline with thiourea. The reaction is usually carried out in an aqueous medium, with a yield of around 80-85%. Commonly, mild heating and the use of a base catalyst like sodium hydroxide are employed for better selectivity and yield.

About

CAS No 1520-27-0
English Name 1-(4-Hydroxyphenyl)thiourea
Molecular Formula C7H8N2OS
Molecular Weight 168.22 g/mol
SMILES C1=CC(=CC=C1NC(=S)N)O
InChIKey QICKOOCQSYZYQB-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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