Compound Q&A
How is 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine (CAS: 13669-70-0) typically synthesized?
Answer
5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine is commonly synthesized by the condensation of 1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocin-5-one with methylamine. The reaction typically proceeds via a condensation reaction using a suitable base, such as sodium ethoxide, in an aprotic solvent like dimethylformamide (DMF). The yield is usually good, around 70-80%, and the product can be isolated by recrystallization from methanol or ethanol.
About
CAS No
13669-70-0
English Name
5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine
Molecular Formula
C17H19NO
Molecular Weight
253.35 g/mol
SMILES
CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3
InChIKey
RGPDEAGGEXEMMM-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36