5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine(CAS: 13669-70-0)

5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine (CAS: 13669-70-0) is a crystalline solid with a molecular weight of approximately 210.24 g/mol. It has moderate solubility in common organic solvents like ethanol and acetone. The compound is moderately reactive, particularly in acidic conditions, and shows good thermal stability up to 200°C. It is a cyclic amide with a benzoxazocine ring system, which contributes to its unique physical and chemical behavior.

5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine is commonly synthesized by the condensation of 1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocin-5-one with methylamine. The reaction typically proceeds via a condensation reaction using a suitable base, such as sodium ethoxide, in an aprotic solvent like dimethylformamide (DMF). The yield is usually good, around 70-80%, and the product can be isolated by recrystallization from methanol or ethanol.

5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine (CAS: 13669-70-0) finds applications in the pharmaceutical industry as a precursor for the synthesis of bioactive compounds. It is also used in the production of certain polymers and in the development of sensor technologies due to its unique chemical structure, which enhances its reactivity and functional properties. Additionally, it may be used in semiconductor applications for its electronic and optical properties.

When handling 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine (CAS: 13669-70-0), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Ensure the use of a fume hood during handling and preparation to minimize inhalation risks. If a spill occurs, it should be cleaned up using absorbent materials, and the area should be well-ventilated. In case of skin contact, rinse with copious amounts of water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information on handling and storage.