Compound Q&A

How is 4,4'-(6-Chloro-2,4-pyrimidinediyl)dimorpholine (CAS: 10244-24-3) typically synthesized?

Answer

4,4'-(6-Chloro-2,4-pyrimidinediyl)dimorpholine
4,4'-(6-Chloro-2,4-pyrimidinediyl)dimorpholine is typically synthesized through a multistep process involving the condensation of 4,4'-dichloropyrimidine with morpholine. The reaction is catalyzed by a Lewis acid such as aluminum chloride. The yield is generally high, and the product is purified by recrystallization from appropriate solvents.

About

CAS No 10244-24-3
English Name 4,4'-(6-Chloro-2,4-pyrimidinediyl)dimorpholine
Molecular Formula C12H17ClN4O2
Molecular Weight 284.75 g/mol
SMILES Clc1cc(nc(n1)N1CCOCC1)N1CCOCC1
InChIKey KIWUTYCMQNZUPX-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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