Compound Q&A
How is 3-chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 80235-01-4) typically synthesized?
Answer
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3-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 80235-01-4) is synthesized by electrophilic chlorination of pyrrolo[2,3-b]pyridine using chlorine gas as the chlorinating agent. The reaction typically occurs under anhydrous conditions in the presence of a Lewis acid catalyst such as aluminum chloride. The yield is around 70-80% with good selectivity for the desired product.
About
CAS No
80235-01-4
English Name
3-chloro-1H-pyrrolo[2,3-b]pyridine
Molecular Formula
C7H5ClN2
Molecular Weight
152.58 g/mol
SMILES
C1=CC2=C(NC=C2Cl)N=C1
InChIKey
PKFDDUMFTQHVFY-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36
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