Compound Q&A
How is tert-Butyl 4-bromoindoline-1-carboxylate (CAS: 885272-46-8) typically synthesized?
Answer
tert-Butyl 4-bromoindoline-1-carboxylate (CAS: 885272-46-8) is synthesized via a bromination reaction of tert-butyl indoline-1-carboxylate with N-bromosuccinimide (NBS) in the presence of AIBN (2,2'-azobisisobutyronitrile) as a radical initiator. The reaction is typically carried out under nitrogen atmosphere to avoid decomposition. The yield is generally around 70-80%.
About
CAS No
885272-46-8
English Name
tert-Butyl 4-bromoindoline-1-carboxylate
Molecular Formula
C13H16BrNO2
Molecular Weight
298.18 g/mol
SMILES
CC(C)(C)OC(=O)N1CCC2=C1C=CC=C2Br
InChIKey
DUZIJTYKDFFQDJ-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36
