Compound Q&A
How is 5-Bromo-6-chloro-4-pyrimidinamine (CAS: 663193-80-4) typically synthesized?
Answer
5-Bromo-6-chloro-4-pyrimidinamine is commonly synthesized through the reaction of 4-chloropyrimidine with bromine in the presence of a catalyst like iron(III) chloride. The reaction yields a mixture that can be purified by recrystallization or column chromatography. The yield is typically around 70-80%, and the reaction is highly selective.
About
CAS No
663193-80-4
English Name
5-Bromo-6-chloro-4-pyrimidinamine
Molecular Formula
C4H3BrClN3
Molecular Weight
208.45 g/mol
SMILES
C1=NC(=C(C(=N1)Cl)Br)N
InChIKey
DQSBRYJETNYGCI-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36
