Compound Q&A

Are there alternatives to 1,3-Bis(bromomethyl)benzene (CAS: 626-15-3) in synthesis?

Answer

1,3-Bis(bromomethyl)benzene
Synthesizers often look for alternatives to 1,3-Bis(bromomethyl)benzene (CAS: 626-15-3) due to its toxicity and reactivity. Brominated aromatics like 2,4-dibromotoluene and 1,3-dibromophenol can be considered as substitutes. Additionally, using less toxic brominating agents such as N-bromosuccinimide (NBS) can be a safer alternative in some reactions. These alternatives can help reduce the environmental impact and improve safety during synthesis.

About

CAS No 626-15-3
English Name 1,3-Bis(bromomethyl)benzene
Molecular Formula C8H8Br2
Molecular Weight 263.96 g/mol
SMILES C1=CC(=CC(=C1)CBr)CBr
InChIKey OXHOPZLBSSTTBU-UHFFFAOYSA-N
Last Updated: 2025-10-17 17:23

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