Compound Q&A
Are there alternatives to 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolyl-L-proline (CAS: 129223-22-9) in synthesis?
Answer
![1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolyl-L-proline](https://static.chemtradehub.com/structs/129/129223-22-9-11c9.webp "1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolyl-L-proline")
While 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolyl-L-proline (CAS: 129223-22-9) is used in certain synthetic processes, there are alternatives such as other protected amino acids or related fluorenylmethoxycarbonyl (Fmoc) protected compounds. Commonly, triisopropylsilylethyl (TIPS) or tert-butyldiphenylsilyl (BzTrt) may be used as alternative protecting groups in peptide synthesis. These alternatives offer similar functionalities but with different reactivity profiles.
About
CAS No
129223-22-9
English Name
1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolyl-L-proline
Molecular Formula
C25H26N2O5
Molecular Weight
434.49 g/mol
SMILES
C1CC(N(C1)C(=O)C2CCCN2C(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)C(=O)O
InChIKey
VRAQFWSWKRNOGU-VXKWHMMOSA-N
Last Updated: 2025-10-17 17:23
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