Compound Q&A

Are there alternatives to 1,3-Dioxan-2-one (CAS: 2453-03-4) in synthesis?

Answer

1,3-Dioxan-2-one
Yes, several alternatives to 1,3-Dioxan-2-one (CAS: 2453-03-4) exist in synthesis. Common substitutes include tetrahydrofuran (THF) and 1,4-dioxane, which offer similar reactivity profiles for certain reactions. However, due to environmental concerns, there is a growing trend towards using more sustainable solvents like ethylenediamine or propylene carbonate. These alternatives are often chosen for their lower toxicity and better biodegradability.

About

CAS No 2453-03-4
English Name 1,3-Dioxan-2-one
Molecular Formula C4H6O3
Molecular Weight 102.09 g/mol
SMILES C1COC(=O)OC1
InChIKey YFHICDDUDORKJB-UHFFFAOYSA-N
Last Updated: 2025-10-17 13:01

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