Compound Q&A

How is 5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile (CAS: 5334-43-0) typically synthesized?

Answer

5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile
5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile is commonly synthesized through a multistep process involving the condensation of an anilide with a nitrile followed by hydrolysis. Common catalysts include acids, and the reaction yields can reach up to 85%. The process is often conducted in organic solvents and requires careful control of temperature and pH to ensure high selectivity.

About

CAS No 5334-43-0
English Name 5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile
Molecular Formula C10H8N4
Molecular Weight 184.2 g/mol
SMILES C1=CC=C(C=C1)N2C(=C(C=N2)C#N)N
InChIKey MAKQREKUUHPPIS-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35

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