5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile(CAS: 5334-43-0)

5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile (CAS: 5334-43-0) is a solid with a crystalline form. Its molecular weight is approximately 228.22 g/mol. This compound is slightly soluble in water and more soluble in organic solvents like ethanol and acetonitrile. Chemically, it is moderately reactive, particularly towards nucleophiles and reducing agents.

5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile is commonly synthesized through a multistep process involving the condensation of an anilide with a nitrile followed by hydrolysis. Common catalysts include acids, and the reaction yields can reach up to 85%. The process is often conducted in organic solvents and requires careful control of temperature and pH to ensure high selectivity.

5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile is primarily used in the pharmaceutical industry for the synthesis of drugs. It also has applications in the polymer industry as a monomer for functional polymers. Additionally, it is used in the production of sensors and semiconductors due to its unique electronic properties.

When handling 5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile (CAS: 5334-43-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be immediately cleaned up using appropriate spill kits, and the area should be thoroughly rinsed. It is also recommended to refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.