Compound Q&A
How is (1S,2R)-1-Amino-2-indanol (CAS: 7480-35-5) typically synthesized?
Answer
(1S,2R)-1-Amino-2-indanol (CAS: 7480-35-5) can be synthesized through a multistep process involving the reduction of indanone with sodium borohydride followed by the addition of ammonia. The reaction conditions should be carefully controlled to achieve high selectivity and yield, typically in the presence of a catalytic amount of sodium hydroxide. The final step involves the removal of by-products and purification using recrystallization.
About
CAS No
7480-35-5
English Name
(1S,2R)-1-Amino-2-indanol
Molecular Formula
C9H11NO
Molecular Weight
149.19 g/mol
SMILES
C1C(C(C2=CC=CC=C21)N)O
InChIKey
LOPKSXMQWBYUOI-BDAKNGLRSA-N
Last Updated: 2025-10-17 07:35
