Compound Q&A
How is 6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, methanesulfonic acid (CAS: 67227-57-0) typically synthesized?
Answer
The compound is typically synthesized via the methylation of 6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol with methanesulfonic anhydride. The reaction is highly selective and yields a high percentage of the desired product. The method involves careful control of reaction temperature and time to ensure optimal yield and purity.
About
CAS No
67227-57-0
English Name
6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, methanesulfonic acid
Molecular Formula
C17H20ClNO6S
Molecular Weight
401.87 g/mol
SMILES
CS(=O)(=O)O.C1CNCC(C2=CC(=C(C(=C21)Cl)O)O)C3=CC=C(C=C3)O
InChIKey
CVKUMNRCIJMVAR-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35
