Compound Q&A
How is 2-(2,2,2-Trifluoroethoxy)phenol (CAS: 160968-99-0) typically synthesized?
Answer
2-(2,2,2-Trifluoroethoxy)phenol is typically synthesized via the reaction of 2,2,2-trifluoroethanol with phenol in the presence of a strong acid catalyst, such as hydrochloric acid. The process involves an etherification step where the hydroxyl group of phenol reacts with the trifluoroethoxy group of the alcohol, yielding the desired product with high selectivity and good yield.
About
CAS No
160968-99-0
English Name
2-(2,2,2-Trifluoroethoxy)phenol
Molecular Formula
C8H7F3O2
Molecular Weight
192.14 g/mol
SMILES
C1=CC=C(C(=C1)O)OCC(F)(F)F
InChIKey
VDWGLBLCECKXRU-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35
