Compound Q&A

How is 5-Iodo-1H-indole (CAS: 16066-91-4) typically synthesized?

Answer

5-Iodo-1H-indole
5-Iodo-1H-indole (CAS: 16066-91-4) can be synthesized through the iodination of 1H-indole using reagents such as iodine and potassium iodide in the presence of a base like sodium hydroxide. The reaction is conducted in an organic solvent to enhance solubility and selectivity. This method provides a high yield of the target compound with good purity, making it a common approach in the laboratory and industry.

About

CAS No 16066-91-4
English Name 5-Iodo-1H-indole
Molecular Formula C8H6IN
Molecular Weight 243.05 g/mol
SMILES C1=CC2=C(C=CN2)C=C1I
InChIKey TVQLYTUWUQMGMP-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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