Compound Q&A

How is 2-Chloro-4-iodo-3-methylpyridine (CAS: 153034-88-9) typically synthesized?

Answer

2-Chloro-4-iodo-3-methylpyridine
2-Chloro-4-iodo-3-methylpyridine is usually synthesized via the reaction of 3-methylpyridine with N-chlorosuccinimide and iodine. The reaction involves electrophilic aromatic substitution. Commonly used catalysts include Lewis acids to promote the reaction. The yield is generally moderate, around 70-80%.

About

English Name 2-Chloro-4-iodo-3-methylpyridine
Molecular Formula C6H5ClIN
Molecular Weight 253.46999999999997 g/mol
SMILES CC1=C(C=CN=C1Cl)I
InChIKey WHCRABJNJRAJIP-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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