Compound Q&A
How is 6-Bromo-1H-indole-2-carboxylic acid (CAS: 16732-65-3) typically synthesized?
Answer
6-Bromo-1H-indole-2-carboxylic acid is typically synthesized via bromination of indole-2-carboxylic acid using N-bromosuccinimide (NBS) in the presence of a suitable oxidizing agent like benzoyl peroxide. The reaction is carried out in a chloroform or dichloromethane solvent at room temperature, yielding a high yield of the desired product with good selectivity.
About
CAS No
16732-65-3
English Name
6-Bromo-1H-indole-2-carboxylic acid
Molecular Formula
C9H6BrNO2
Molecular Weight
240.06 g/mol
SMILES
C1=CC2=C(C=C1Br)NC(=C2)C(=O)O
InChIKey
SVBVYRYROZWKNJ-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48
