How is (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate hydrate (CAS: 55812-90-3) typically synthesized?

This compound is typically synthesized via a multi-step process involving the reduction of a fluoro-pregnanone, followed by acetylation and hydration. The synthesis involves the use of a palladium catalyst for the reduction step, ensuring high selectivity and yield. The final step involves the addition of acetic acid and water to form the hydrate.