Compound Q&A
How is 3-Bromo-8-chloroimidazo[1,2-a]pyrazine (CAS: 143591-61-1) typically synthesized?
Answer
![3-Bromo-8-chloroimidazo[1,2-a]pyrazine](https://static.chemtradehub.com/structs/143/143591-61-1-ea58.webp "3-Bromo-8-chloroimidazo[1,2-a]pyrazine")
3-Bromo-8-chloroimidazo[1,2-a]pyrazine is commonly synthesized via the reaction of 8-chloroimidazo[1,2-a]pyrazine with N-bromosuccinimide (NBS) in the presence of a suitable photoinitiator. This method provides good yields and high regioselectivity. Other synthetic routes involve the use of bromine in the presence of a Lewis acid, leading to the desired product with high purity.
About
CAS No
143591-61-1
English Name
3-Bromo-8-chloroimidazo[1,2-a]pyrazine
Molecular Formula
C6H3BrClN3
Molecular Weight
232.47 g/mol
SMILES
C1=CN2C(=CN=C2C(=N1)Cl)Br
InChIKey
MCEGPQSPRNOFMG-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48
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