Compound Q&A

How is 3-(1-Piperazinyl)phenol (CAS: 59817-32-2) typically synthesized?

Answer

3-(1-Piperazinyl)phenol
3-(1-Piperazinyl)phenol can be synthesized via the reaction of p-phenol with 1-piperazinecarboxylic acid. This typically involves a condensation reaction followed by acid workup to yield the product with good selectivity and moderate yield. A suitable catalyst, such as a Lewis acid, may be used to enhance reactivity.

About

CAS No 59817-32-2
English Name 3-(1-Piperazinyl)phenol
Molecular Formula C10H14N2O
Molecular Weight 178.23 g/mol
SMILES C1CN(CCN1)C2=CC(=CC=C2)O
InChIKey AYGYICRITMSJOC-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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