Compound Q&A

How is Methyl (2Z)-3-amino-2-butenoate (CAS: 21731-17-9) typically synthesized?

Answer

Methyl (2Z)-3-amino-2-butenoate
Methyl (2Z)-3-amino-2-butenoate is typically synthesized via a one-pot reaction between methyl vinyl ketone and ammonia in the presence of a strong base like sodium hydroxide. The reaction is selective and yields the (2Z)-isomer with good efficiency. The product is isolated and purified by recrystallization from an appropriate solvent.

About

CAS No 21731-17-9
English Name Methyl (2Z)-3-amino-2-butenoate
Molecular Formula C5H9NO2
Molecular Weight 115.13 g/mol
SMILES COC(=O)\C=C(\C)N
InChIKey XKORCTIIRYKLLG-ARJAWSKDSA-N
Last Updated: 2025-10-16 16:48

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