Methyl (2Z)-3-amino-2-butenoate(CAS: 21731-17-9)

Methyl (2Z)-3-amino-2-butenoate is a crystalline solid with a molecular weight of approximately 131.15 g/mol. It is slightly soluble in water and soluble in organic solvents like ethanol and acetone. It is moderately reactive, particularly towards nucleophiles and reducing agents. The compound is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

Methyl (2Z)-3-amino-2-butenoate is typically synthesized via a one-pot reaction between methyl vinyl ketone and ammonia in the presence of a strong base like sodium hydroxide. The reaction is selective and yields the (2Z)-isomer with good efficiency. The product is isolated and purified by recrystallization from an appropriate solvent.

Methyl (2Z)-3-amino-2-butenoate is used in the pharmaceutical industry for the synthesis of certain drugs due to its amino functionality. It is also utilized in the polymer industry for the modification of polymer properties and in the sensing industry for the development of specific chemical sensors. Additionally, it has potential applications in the semiconductor industry for certain chemical processes.

When handling Methyl (2Z)-3-amino-2-butenoate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood due to its potential irritancy. Spills should be cleaned up with caution using appropriate absorbent materials. The material safety data sheet (MSDS) should be consulted for detailed safety information and emergency procedures.