Compound Q&A
How is (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate (CAS: 16321-99-6) typically synthesized?
Answer
This compound can be synthesized via the condensation of 2-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran with acetic anhydride. Commonly, this is catalyzed by a tertiary amine base such as triethylamine. The reaction typically proceeds with high yield and good selectivity, providing a diacetate product.
About
CAS No
16321-99-6
English Name
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
Molecular Formula
C16H18ClN5O7
Molecular Weight
427.8 g/mol
SMILES
CC(=O)OCC1C(C(C(O1)N2C=NC3=C2N=C(N=C3Cl)N)OC(=O)C)OC(=O)C
InChIKey
HLVGVJFVAKPFOZ-SDBHATRESA-N
Last Updated: 2025-10-16 16:48
