Are there alternatives to Beclomethasone in synthesis?

Beclomethasone (CAS: 4419-39-0) can be synthesized using various methods. For instance, alternative reagents such as 17α-acetylene can be used instead of 17α-acetylation. Other analogs like fluticasone propionate can also be considered as alternatives, offering similar anti-inflammatory effects but with potentially different pharmacokinetic properties. These alternatives may offer advantages in terms of potency, bioavailability, or side-effect profile.