Compound Q&A
How is Methyl 2-chloro-6-methylpyrimidine-4-carboxylate (CAS: 89793-11-3) typically synthesized?
Answer
Methyl 2-chloro-6-methylpyrimidine-4-carboxylate (CAS: 89793-11-3) is typically synthesized via the condensation of methyl 4-carboxy-2-chloropyrimidine-6-carbaldehyde with 2-methylbenzene-1,4-diol in the presence of a base like sodium hydroxide. The reaction is carried out in an aprotic solvent such as dimethylformamide (DMF) under mild conditions, providing a yield of about 75%. The reaction is selective and produces the desired product with high purity.
About
CAS No
89793-11-3
English Name
Methyl 2-chloro-6-methylpyrimidine-4-carboxylate
Molecular Formula
C7H7ClN2O2
Molecular Weight
186.598 g/mol
SMILES
CC1=CC(=NC(=N1)Cl)C(=O)OC
InChIKey
ZNPORLVPCMFKOR-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39
