Compound Q&A

How is 2,5-Difluorobenzoyl chloride (CAS: 35730-09-7) typically synthesized?

Answer

2,5-Difluorobenzoyl chloride
2,5-Difluorobenzoyl chloride is typically synthesized by the chlorination of 2,5-difluorobenzoic acid in the presence of thionyl chloride. This process involves refluxing the mixture under anhydrous conditions to ensure high yield and selectivity. The reaction is carried out in a fume hood to manage the generation of toxic gases.

About

CAS No 35730-09-7
English Name 2,5-Difluorobenzoyl chloride
Molecular Formula C7H3ClF2O
Molecular Weight 176.55 g/mol
SMILES C1=CC(=C(C=C1F)C(=O)Cl)F
InChIKey RLRUKKDFNWXXRT-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39

Related Q&A

Compound Q&A

What are the physical and chemical properties of 2,5-Difluorobenzoyl chloride (CAS: 35730-09-7)?

2,5-Difluorobenzoyl chloride is a white crystalline solid with a molecular weight of approximately 2...

Compound Q&A

What industries use 2,5-Difluorobenzoyl chloride (CAS: 35730-09-7)?

2,5-Difluorobenzoyl chloride is widely used in the pharmaceutical industry for the synthesis of vari...

Compound Q&A

What precautions should be taken when handling 2,5-Difluorobenzoyl chloride (CAS: 35730-09-7)?

When handling 2,5-Difluorobenzoyl chloride, it is crucial to wear appropriate personal protective eq...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...