Compound Q&A
How is 2-Bromo-6-(bromomethyl)pyridine (CAS: 83004-10-8) typically synthesized?
Answer
2-Bromo-6-(bromomethyl)pyridine is typically synthesized via a reduction of 2-chloro-6-(chloromethyl)pyridine followed by bromination. This process often uses a palladium catalyst in the presence of a basic solvent. The reaction is conducted under mild conditions to ensure high selectivity and yield. Commonly, sodium borohydride is used for the initial reduction step, followed by Br2 in the presence of a base like NaHCO3 or NaOH.
About
CAS No
83004-10-8
English Name
2-Bromo-6-(bromomethyl)pyridine
Molecular Formula
C6H5Br2N
Molecular Weight
250.92 g/mol
SMILES
BrCc1cccc(Br)n1
InChIKey
LSRDTCMNGSMEEI-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39
