Compound Q&A

How is 2',4-Dihydroxy-4',6'-dimethoxychalcone (CAS: 37308-75-1) typically synthesized?

Answer

2',4-Dihydroxy-4',6'-dimethoxychalcone
2',4-Dihydroxy-4',6'-dimethoxychalcone is usually synthesized via a condensation reaction between 2-hydroxy-4',6'-dimethoxyacetophenone and a suitable aromatic aldehyde in the presence of an acid catalyst such as acetic acid. The reaction typically proceeds with good yield and selectivity.

About

CAS No 37308-75-1
English Name 2',4-Dihydroxy-4',6'-dimethoxychalcone
Molecular Formula C17H16O5
Molecular Weight 300.31 g/mol
SMILES COC1=CC(=C(C(=C1)OC)C(=O)C=CC2=CC=C(C=C2)O)O
InChIKey UXUFMIJZNYXWDX-VMPITWQZSA-N
Last Updated: 2025-10-13 19:39

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