Compound Q&A

How is (2,2-Difluoro-1,3-benzodioxol-5-yl)methanol (CAS: 72768-97-9) typically synthesized?

Answer

(2,2-Difluoro-1,3-benzodioxol-5-yl)methanol
(2,2-Difluoro-1,3-benzodioxol-5-yl)methanol can be synthesized via the reduction of 2,2-difluoro-1,3-benzodioxol-5-one. This can be achieved using hydrogen gas in the presence of a catalyst like palladium on carbon. The reaction is typically carried out in a solvent such as methanol or ethanol, and the yield can be up to 85%.

About

CAS No 72768-97-9
English Name (2,2-Difluoro-1,3-benzodioxol-5-yl)methanol
Molecular Formula C8H6F2O3
Molecular Weight 188.13 g/mol
SMILES C1=CC2=C(C=C1CO)OC(O2)(F)F
InChIKey PJPDSEYHEHGLOH-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39

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