(2,2-Difluoro-1,3-benzodioxol-5-yl)methanol(CAS: 72768-97-9)

(2,2-Difluoro-1,3-benzodioxol-5-yl)methanol is a colorless crystalline solid with a molecular weight of 228.08 g/mol. It has a low water solubility and is moderately soluble in organic solvents. The compound is known for its reactivity in nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a cool, dark place to avoid photochemical degradation.

(2,2-Difluoro-1,3-benzodioxol-5-yl)methanol can be synthesized via the reduction of 2,2-difluoro-1,3-benzodioxol-5-one. This can be achieved using hydrogen gas in the presence of a catalyst like palladium on carbon. The reaction is typically carried out in a solvent such as methanol or ethanol, and the yield can be up to 85%.

(2,2-Difluoro-1,3-benzodioxol-5-yl)methanol is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drug molecules. It is also utilized in the polymer industry for the preparation of functional polymers, and in the semiconductor industry for the development of organic semiconductors.

When handling (2,2-Difluoro-1,3-benzodioxol-5-yl)methanol, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. In case of a spill, the area should be immediately cleaned up using appropriate absorbent materials. For more detailed safety information, refer to the Safety Data Sheet (SDS).