Compound Q&A
How is 3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 719268-92-5) typically synthesized?
Answer
3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is typically synthesized via a coupling reaction starting from 3-fluoropyridine and 1,3,2-dioxaborinane in the presence of a palladium catalyst, such as Pd(PPh3)2Cl2, with a base like cesium carbonate. This process provides high yield and good selectivity, making it a reliable method for its synthesis.
About
CAS No
719268-92-5
English Name
3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Molecular Formula
C11H15BFNO2
Molecular Weight
223.06 g/mol
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC(=CN=C2)F
InChIKey
VFMTUTYBMBTIGA-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39
