Compound Q&A
How is trans-4-(2-Methyl-2-propanyl)cyclohexanol (CAS: 21862-63-5) typically synthesized?
Answer
trans-4-(2-Methyl-2-propanyl)cyclohexanol is typically synthesized through a Wittig reaction or a modified Robinson annulation. The Wittig reaction involves the reaction of phenylphosphonium bromide with cyclohexanone in the presence of a Lewis acid catalyst. The modified Robinson annulation involves the condensation of cyclohexanone with 2-methyl-2-propanol followed by base catalyzed cyclization.
About
CAS No
21862-63-5
English Name
trans-4-(2-Methyl-2-propanyl)cyclohexanol
Molecular Formula
C10H20O
Molecular Weight
156.27 g/mol
SMILES
O[C@H]1CC[C@H](C(C)(C)C)CC1
InChIKey
CCOQPGVQAWPUPE-KYZUINATSA-N
Last Updated: 2025-10-13 17:50