Compound Q&A

How is 1-(Bromomethyl)-3,5-bis(trifluoromethyl)benzene (CAS: 32247-96-4) typically synthesized?

Answer

1-(Bromomethyl)-3,5-bis(trifluoromethyl)benzene
1-(Bromomethyl)-3,5-bis(trifluoromethyl)benzene is usually synthesized via the reaction of 3,5-bis(trifluoromethyl)benzyl bromide with 1-bromo-3,5-difluorobenzene. This process involves the use of a Lewis acid catalyst to promote the reaction. The yield and selectivity of the product can be improved by optimizing reaction conditions and using appropriate solvents.

About

CAS No 32247-96-4
English Name 1-(Bromomethyl)-3,5-bis(trifluoromethyl)benzene
Molecular Formula C9H5BrF6
Molecular Weight 307.03099999999995 g/mol
SMILES C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)CBr
InChIKey ATLQGZVLWOURFU-UHFFFAOYSA-N
Last Updated: 2025-10-13 17:50

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