Compound Q&A

How is Ethyl 2,4-dimethyl-1,3-thiazole-5-carboxylate (CAS: 7210-77-7) typically synthesized?

Answer

Ethyl 2,4-dimethyl-1,3-thiazole-5-carboxylate
Ethyl 2,4-dimethyl-1,3-thiazole-5-carboxylate (CAS: 7210-77-7) is typically synthesized using a multistep reaction involving the condensation of 2,4-dimethylthiazole-5-carboxylic acid with ethylamine, followed by amination. Commonly, this reaction is catalyzed by a strong base like sodium hydride, and the yield is around 85%. The product is then purified by recrystallization or chromatography.

About

CAS No 7210-77-7
English Name Ethyl 2,4-dimethyl-1,3-thiazole-5-carboxylate
Molecular Formula C8H11NO2S
Molecular Weight 185.25 g/mol
SMILES CCOC(=O)C1=C(N=C(S1)C)C
InChIKey BXOIIRQIGYJTTB-UHFFFAOYSA-N
Last Updated: 2025-10-13 15:08

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