Compound Q&A

How is 4-(Trifluoromethoxy)benzylamine (CAS: 93919-56-3) typically synthesized?

Answer

4-(Trifluoromethoxy)benzylamine
4-(Trifluoromethoxy)benzylamine is typically synthesized via the reduction of 4-(trifluoromethoxy)benzyl nitrile using sodium borohydride or lithium aluminium hydride as a reducing agent. The reaction is performed in anhydrous solvents like tetrahydrofuran (THF) under inert atmosphere to ensure high selectivity and yield.

About

CAS No 93919-56-3
English Name 4-(Trifluoromethoxy)benzylamine
Molecular Formula C8H8F3NO
Molecular Weight 191.15 g/mol
SMILES C1=CC(=CC=C1CN)OC(F)(F)F
InChIKey DBGROTRFYBSUTR-UHFFFAOYSA-N
Last Updated: 2025-10-13 15:08

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